Main Article Content

Abstract

Antibiotics are therapies used in cases of infection. Inappropriate use of antibiotics will cause the impact of resistance. Antibiotic use studies need to be done as a step to reduce this impact. The purpose of this study was to determine the practice of using antibiotics by measuring the quantity using the Defined Daily Dose (DDD) and DU90% method in inpatients with a diagnosis of Community-Acquired Pneumonia (CAP) at PKU Muhammadiyah Gamping Hospital. This study is a retrospective study on inpatients of PKU Muhammadiyah Gamping Hospital in 2016-2018. Data was obtained from patient medical records. The results showed a change in the pattern of antibiotic used in 2016-2018. Ceftriaxone and ceftazidime are the most widely used antibiotics. Ceftriaxone with a DDD value of 12.59; 22.49; 23.53 / 100 bed-days and ceftazidime with a DDD value of 17.09; 12.98; 10.59 / 100 bed-days. Antibiotics that are included in DU 90% are Ceftriaxone, Ceftazidime, Cefixime and Levofloxacine. The conclusion of this study is that there is a change in the pattern of antibiotic use in cases of Community-Acquired Pneumonia (CAP) in 2016-2018.


 

Keywords

Antibiotic Community Acquired Pneumonia Defined Daily Dose DU90%

Article Details

References

  1. Ambami, S. (2020). Evaluasi Penggunaan Antibiotik dengan Metode ATC/DDD pada Pasien Pneumonia di RSUD Jombang Periode Januari-Desember 2019 Etheses of Maulana Malik Ibrahim State Islamic University. http://etheses.uin-malang.ac.id/19089/
  2. Elvina, R., Rahmi, N., & Oktavira, S. A. (2018). Evaluasi Penggunaan Antibiotik pada Pasien Community-Acquired Pneumonia (CAP) di Instalasi Rawat Inap Rumah Sakit “X” Jakarta. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 14(1), 64–74.
  3. Figueiredo-Mello, C., Naucler, P., Negra, M. D., & Levin, A. S. (2018). Ceftriaxone versus ceftriaxone plus a macrolide for community-acquired pneumonia in hospitalized patients with HIV/AIDS: A randomized controlled trial. Clinical Microbiology and Infection, 24(2), 146–151. https://doi.org/10.1016/j.cmi.2017.06.013
  4. Hasegawa, S., Shiraishi, A., Yaegashi, M., Hosokawa, N., Morimoto, K., & Mori, T. (2019). Ceftriaxone versus ampicillin/sulbactam for the treatment of aspiration-associated pneumonia in adults. Journal of Comparative Effectiveness Research, 8(15), 1275–1284. https://doi.org/10.2217/cer-2019-0041
  5. Kemenkes. (2018). Laporan Hasil Riset Kesehatan Dasar (Riskesdas) | Badan Penelitian dan Pengembangan Kesehatan. https://www.litbang.kemkes.go.id/laporan-riset-kesehatan-dasar-riskesdas/
  6. Muhammad, O. R., & Mutmainah, N. (2018). Evaluasi Penggunaan Antibiotik dengan Metode ATC/DDD pada Pasien Pneumonia di Instalasi Rawat Inap RSUD Dr. Moewardi Tahun 2017 (Doctoral dissertation, Universitas Muhammadiyah Surakarta).
  7. Nugroho, F., Utami, P. I., & Astuti, I. Y. (2011). Evaluasi Penggunaan Antibiotik Pada Penyakit Pneumonia Di Rumah Sakit Umum Daerah Purbalingga. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 8(01), Article 01. https://doi.org/10.30595/pji.v8i1.603
  8. Olson, G., & Davis, A. M. (2020). Diagnosis and Treatment of Adults With Community-Acquired Pneumonia. JAMA, 323(9), 885. https://doi.org/10.1001/jama.2019.21118
  9. Prakoso, D., Posangi, J., & Nangoy, E. (2018). Gambaran dan Rasionalitas Penggunaan Antibiotik pada Pasien Dewasa dengan Community Acquired Pneumonia di RSUP Prof. Dr. R. D. Kandou Manado Periode Juni 2017-Mei 2018. EBiomedik, 6(2), Article 2. https://doi.org/10.35790/ebm.6.2.2018.22156
  10. Prananingtyas, A. (2017). Evaluasi Terapi Penggunaan Antibiotik Pada Pasien Pneumonia Rawat Inap Di Rumah Sakit Khusus Paru Respira Yogyakarta Tahun 2015. http://repository.umy.ac.id/handle/123456789/15538
  11. Prasetyo, E. Y., & Kusumaratni, D. A. (2019). Evaluasi Penggunaan Antibiotik Pada Pasien Pneumonia Rawat Inap Di Rs Dkt Kota Kediri Dengan Metode Atc-Ddd Tahun 2018. Prosiding Artikel Seminar Nasional Farmasi, 0(0), Article 0. https://prosidingonline.iik.ac.id/index.php/semfarm/article/view/124
  12. Putri, R. M., & Hasan, H. (2014). Tinjauan Imunologi Pneumonia pada Pasien Geriatri. Cermin Dunia Kedokteran, 41(1), 14–18.
  13. Sama, I. and Mutmainah, N. (2018) ‘Evaluasi Penggunaan Antibiotik Pada Pasien Community-Acquired Pneumonia Rawat Inap Di Rsud Dr. Moewardi Tahun 2016’. Universitas Muhammadiyah Surakarta.
  14. Torres, A., Peetermans, W. E., Viegi, G., & Blasi, F. (2013). Risk factors for community-acquired pneumonia in adults in Europe: A literature review. Thorax, 68(11), 1057–1065. https://doi.org/10.1136/thoraxjnl-2013-204282
  15. Utami, E. R. (2011). Antibiotika, Resistensi, Dan Rasionalitas Terapi. El-Hayah : Jurnal Biologi, 1(4), Article 4. https://doi.org/10.18860/elha.v1i4.1783
  16. Wulandari, D. N. (2016). Efektivitas Penggunaan Antibiotik Ceftriaxone Pada Pasien Pneumonia Dewasa Di Instalasi Rawat Inap Rsud Dr. Moewardi Surakarta Tahun 2014—2015. https://digilib.uns.ac.id/dokumen/54482/Efektivitas-Penggunaan-Antibiotik-Ceftriaxone-Pada-Pasien-Pneumonia-Dewasa-Di-Instalasi-Rawat-Inap-Rsud-Dr-Moewardi-Surakarta-Tahun-2014-2015