Article Sidebar

Submitted
Jul 4, 2020
Published
Apr 28, 2022
Download
Pdf
Statistic
Read Counter : 1735 Download : 4914

Downloads

Download data is not yet available.

Main Article Content

Abstract

Kersen (Muntingia calabura L.) is known as a plant that is often used as a tree to absorb air pollution and shade on the roadside. Low economic value and public knowledge about the benefits of cherry as a medicinal and food ingredient is still minimal. The part that can be used as a medicinal ingredient comes from cherry leaves. The purpose of this review article is to provide information related to the chemical content and pharmacological activity of cherry leaves that can treat various diseases. The method used in making this article review is a literature study. The literature sources in this article review were obtained from national journals and international journals published in the last 10 years (2010-2020), which were carried out online through the search engines Google Scholar, Pubmed, and NCBI, using the keywords "Kersen leaves", "Activities cherry leaf”, “Pharmacological activity of Muntingia calabura”, “Chemical content of cherry leaf”, “Muntingia calabura L.”. Journals that enter the inclusion criteria are national and international journals that discuss the pharmacological activity and chemical content of cherry leaves, journals published in the last 10 years (2010-2020), and journals in full text. The chemical constituents contained in cherry leaves are flavonoids, saponins, tannins, and terpenoids. Cherry leaves are scientifically proven to have several pharmacological activities as antidiabetic, antioxidant, antibacterial, anthelmintic, antihyperlipidemic, and anti-inflammatory.

Keywords

Kersen Leaves Muntingia calabura L Chemical content Pharmacological activity

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

References

  1. Aligita, W., Susilawati, E., Sukmawati, I. K., Holidayanti, L., & Riswanti, J. (2018). Antidiabetic activities of Muntingia calabura L. leaves water extract in type 2 diabetes mellitus animal models. Indonesian Biomedical Journal, 10(2), 165–170. https://doi.org/10.18585/inabj.v10i2.405
  2. Calabura, M. (2018). Science & Technology Indonesia Antidiabetic Activity Test Of Ethanolic Seri Leave ’ s ( Muntingia Calabura L .) Ex- tract In Male Rats Induced By Alloxan. 3, 7–13
  3. Dan, I., Daya, U. J. I., Ekstrak, A., & Kersen, D. (2013). Isolasi Dan Uji Daya Antimikroba Ekstark Daun Kersen (Muntingia calabura L). Jurnal MIPA, 35(2).
  4. Fahdi, F. (2018). Uji Aktivitas Antibakteri Ekstrak Daun Kersen (Muntingia calabura L.) terhadap Pertumbuhan Bakteri Staphylococcus aureus & Escherichia coli. Public Health Community STIKes Delihusada Delitua, ISSN 2301-7465.
  5. Febrina, M., & Sari, S. F. (2019). Pengaruh Pemberian Infusa Daun Kersen (Muntingia calabura L.) Terhadap Kadar Glukosa Darah Mencit Putih (Mus musculus) Yang Diberi Beban Glukosa. Jurnal Penelitian Farmasi Indonesia, 8(2), 2.
  6. Handayani, F., Siswanto, E., & Pangesti, L. (2015). Uji Aktivitas Ekstrak Etanol Daun Kersen (Muntingia calabura L.) terhadap Penyembuhan Luka Bakar pada Kulit Mencit Putih Jantan (Mus musculus). Jurnal Ilmiah Ibnu Sina, 1(2), 133–139.
  7. Handayani, V. (2016). Pengujian Aktivitas Antibakteri Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Terhadap Bakteri Penyebab Jerawat. Jurnal Fitofarmaka Indonesia, 2(1), 94–96. https://doi.org/10.33096/jffi.v2i1.186
  8. Hasanah, M., Andriani, N., & Noprizon, N. (2016). Perbandingan Aktivitas Antioksidan Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Hasil Ekstraksi Maserasi Dan Refluks. Scientia : Jurnal Farmasi Dan Kesehatan, 6(2), 84. https://doi.org/10.36434/scientia.v6i2.52
  9. I dewa ayu, & Sri Suryaningsih (2018). Uji Efek Analgesik Ekstrak Etanol Daun Kersen ( Muntingia calabura L.)Pada Mencit (Mus musculas). Jurnal Ilmiah Farmasi, 2(2), 147–153.
  10. Maifitrianti, D. (2019). Aktifitsa Antiinflamasi Fraksi-Fraksi Ekstrak Etanol 95% Dari Daun Kersen (Muntingia calabura L.) Pada Tikus Putih Jantan. SSRN Electronic Journal, 5(564), 1–19. https://doi.org/10.4324/9781315853178
  11. Mhd. Riza Marjoni, & Afrinaldi, D. N. A. (2015). Kandungan Total Fenol Dan Aktivitas Antioksidan Ekstrak Air Daun Kersen (Muntingia calabura L.). Yarsi Medical Journal, 23(32), 187–1962.
  12. Puspasari, A. F., Agustini, S. M., & Illahika, A. P. (2016). Pengaruh Ekstrak Daun Kersen (Muntingia Calabura L.) Terhadap Profil Lipid Mencit Putih (Mus Musculus) Jantan Yang Diinduksi Minyak Jelantah. Saintika Medika, 12(1), 49. https://doi.org/10.22219/sm.v12i1.5260
  13. Puspitasari, A. D., & Prayogo, L. S. (2016). Pengaruh Waktu Perebusan terhadap Kadar Flavonoid Total Daun Kersen (Muntingia calabura L.). Inovasi Teknik Kimia, 1(2), 104–108.
  14. Puspitasari, A. D., & Wulandari, R. L. (2017). Aktivitas Antioksidan dan Penetapan Kadar Flavonoid Total Ekstrak Etil Asetat Daun Kersen (Muntingia calabura L.). Jurnal Pharmascience, 4(2), 167–175. https://doi.org/10.20527/jps.v4i2.5770.
  15. Putri, A., Yuliet, & Khildah, K. (2018). Efektivitas ekstrak daun kersen (. Biocelebes, 12(1), 1–8.
  16. Rahman, S., Wati, A., & Asariningtyas, E. M. (2017). Efek Antiinflamasi Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Pada Mencit (Mus musculus) Safriani. As-Syifaa, 09(01), 51–57.
  17. Ramadhani, N., & Sumiwi, S. A. (2015). Aktivitas Antiinflamasi Berbagai Tanaman Diduga Berasal Dari Flavonoid. Farmaka, 14(2), 111–123.
  18. Riskesdas. (2010). Riset Kesehatan Dasar Tahun2010. Riskesdas 2010, 1–446. https://doi.org/1 Desember 2013.
  19. Riswanto dan Susiyanto. (2016). Uji Efek Analgesik Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Pada Mencit Putih Jantan (Mus musculus) Dengan Induksi Nyeri Asam Asetat. Jurnal Ilmiah Manutung, 2(2), 147–153.
  20. Sakti, A. A., Kustantinah, Nurcahyo, R. W., Baliarti, E., & Suwignyo, B. (2020). In vitro anthelmintic activity of kersen leaf (Muntingia calabura L.) infusion against to Haemonchus contortus worm. IOP Conference Series: Earth and Environmental Science, 462(1). https://doi.org/10.1088/1755-1315/462/1/012005
  21. Sapra, A., Riski, R., Hidayah, N., Tinggi, S., Farmasi, I., Perintis, J., Km, K., & Selatan, S. (2019). Diffusion and Irritation Test of Solid Lipid Microparticle Cream Loaded Ethanol Extract of Kersen Leaf ( Muntingia calabura L .) Uji Difusi dan Iritasi Krim Solid Lipid Microparticle Ekstrak Etanol Daun Kersen ( Muntingia calabura L .). Pharmaceutical and Medicinal Science, 4(1), 6–9.
  22. Sartika, W. A. D., & Permatasari, A. (2018). Formulasi Sabun Anti Jerawat Ekstrak Etanol Daun Kersen (Muntingia calabura L.). Journal of Pharmaceutical Care Anwar Medika, 1(1). https://doi.org/10.36932/j-pham.v1i1.6
  23. Senet, M. R. M., Parwata, I. M. O. A., & Sudiarta, I. W. (2017). Kandungan Total Fenol Dan Flavonoid Dari Buah Kersen (Muntingia calabura L.) Serta Aktivitas Antioksidannya. Jurnal Kimia, 187. https://doi.org/10.24843/jchem.2017.v11.i02.p14
  24. Senthilnathan, M., Jahan, A., Srinivas, K., Kumar, P. R., & Srinivasa, G. (2019). In vitro anthelmintic activity of Muntingia calabura leaf extract against Haemonchus contortus. Journal of Pharmacognosy and Phytochemistry, 8(6), 793–797.
  25. Sulaiman, A. Y., Astuti, P., & Permana Shita, A. D. (2017). Uji Antibakteri Ekstrak Daun Kersen (Muntingia Calabura L.) Terhadap Koloni Streptococcus viridans. Indonesian Journal for Health Sciences, 1(2), 1. https://doi.org/10.24269/ijhs.v1i2.590
  26. Tropika, J. E., Kedokteran, F., Universitas, H., & Kuala, S. (2017). Efektivitas Pemberian Ekstrak Daun Kersen (Muntingia calabura L.) Terhadap Struktur Mikroskopis Sel Beta Pankreas Tikus Hiperglikemik. Jurnal EduBio Tropika, 5(1).
  27. Ulina, N., Turnip, M. B., Arum, C., & Cahya, D. (2020). Uji Efektivitas Antibakteri Sediaan Salep Dari Ekstrak Daun Kersen ( Muntingia calabura L . ) Terhadap Bakteri Staphylococcus aureus. 2(2), 85–90.
  28. Widiastuti, R., Sary, R. R., & Aini, R. (2013). Aktivitas Antelmintika Infusa Daun Kersen ( Muntingia calabura Linn ) Terhadap Cacing Ascaridia galli Schrank Secara In Vitro. Pharmauho Volume 3, Majalah Farmasi, Sains, Dan Kesehatan, 3(1), 39–42.