Article Sidebar

Submitted
Feb 20, 2021
Published
Dec 1, 2022
Download
Pdf
Statistic
Read Counter : 549 Download : 674

Downloads

Download data is not yet available.

Main Article Content

Abstract

Tuberculosis is an infectious disease caused by the bacteria Mycobacterium Tuberculosis which has a rod shape and is acid-resistant. The prolonged consumption of anti-tuberculosis drugs can cause serious side effects. Side effects from the consumption of anti-tuberculosis drugs, namely the risk of hepatotoxicity, which is marked by an increase in the SGOT / SGPT value. This study aimed to determine the relationship between the duration of use, dosage and side effects of anti-tuberculosis drugs in tuberculosis patients, which had an effect on the SGOT / SGPT value at RSI Sultan Agung Semarang. This research is an analytical observational study with a cross-sectional design. The sample was 96 patients, and data collection was carried out in January-November 2020 at RSI Semarang. The instrument used in this study was patient medic record data. This study uses the Chi-Square test. The Chi-Square test results in 0.000 (p <0.05) so that it could be stated that there was a relationship between the use and side effects on the SGOT / SGPT value.

Keywords

Tuberculosis Intensive phase SGOT/SGPT value

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

References

  1. Aminah, S. (2013). Perbedaan Kadar SGOT , SGPT , Ureum , dan Kreatinin Pada Penderita TB Paru Setelah Enam Bulan Pengobatan Different Levels SGOT , SGPT , urea , and creatinine Pulmonary TB In Six Months After Treatment. Jurnal Analis Kesehatan, 2(1), 260–269. https://ejurnal.poltekkes-tjk.ac.id/index.php/JANALISKES/article/view/432/406
  2. Andayani, S., & Astuti, Y. (2020). Prediksi Kejadian Penyakit Tuberkolosis Paru Berdasarkan Usia di Kabupaten Ponorogo Tahun 2016-2020. Indonesian Journal for Health Sciences ISSN 2549-2721 (Print), ISSN 2549-2748 (Online), 01(02), 29–33. https://journal.umpo.ac.id/index.php/IJHS/article/view/482
  3. Dasopang, E. V. A. S., Hasanah, F., Fauziah, I. D. A., & Bakri, T. K. (2020). Potential Side Effects of Medicine on Patients with Tuberculosis Fixed-Dose Combination In Dr. Pirngadi Hospital, Medan. Jurnal https://doi.org/10.24815/jn.v20i1.15285 , 20(1), 10-14. https://doi.org/10.24815/jn.v20i1.15285
  4. Depkes. (2016). Profil Kesehatan Indonesia Tahun 2015, Kementrian Kesehatan Indonesia. In Pusdatin.Kemenkes.Go.Id. https://www.kemkes.go.id/article/view/16091600001/-profil-kesehatan-indonesia-tahun-2015.html
  5. Dhita Yuniar, K., Sidi, M., & Sari, E. P. (2015). Gambaran Kadar Sgpt (Serum Glutamic Pyruvic Transaminase) Pada Perokok Aktif. Jurnal Analis Kesehatan, 2(1). https://ejournal.unsrat.ac.id/index.php/ebiomedik/article/view/11048
  6. Erlangga, K. B. (2019). Hubungan kadar enzim sgot dan sgpt pada pengobatan fase lanjut penderita tuberkulosis di rsud budhi asih. Karya Tulis Ilmiah, 9, 97–107. http://rsudbudhiasih.jakarta.go.id/elibrary/upload/KTI KRESNA - 1010161054.
  7. Kemenkes, R. (2011). Pedoman nasional pengendalian tuberkulosis. Kementerian Kesehatan Republik Indonesia, 1–80. https://tbindonesia.or.id/pustaka/pedoman/umum/pedoman-nasional-pelayanan-kedokteran-tata-laksana-tuberkulosis/
  8. Lomanorek, V. Y., Assa, Y. A., & Mewo, Y. M. (2016). Gambaran Kadar Serum Serum Glutamic Oxaloacetic Transaminase (Sgot) Pada Perokok Aktif Usia > 40 Tahun. Jurnal E-Biomedik, 4(1). https://ejournal.unsrat.ac.id/index.php/ebiomedik/article/view/11046
  9. Musdalipah, Eny, N., Karmilah, & Fakhrurazi, M. (2018). Efek Samping Obat Anti Tuberkulosis ( Oat ) Dan Penanganannya Pada Pasien Tuberkulosis ( Tb ) Di Pukesmas Perumnas Kota Kendari. Jurnal Ilmiah Manuntung, 4(1), 67–73. https://jurnal.akfarsam.ac.id/index.php/jim/article/view/144
  10. Nuroini, F., Rahayu, S. E., & Sukeksi, A. (2017). Hubungan Kadar Sgot-Sgpt Pada Pasien Tb Pengobatan Fase Awal Di Puskesmas Pati. Jurnal Keperawatan Indonesia. http://repository.unimus.ac.id/3235/
  11. Prameswari, A. (2018). The Evaluation of Directly Observed Treatment Short-Course (DOTS) Implementation for TB in Hospital X. Jurnal Medicoeticolegal Dan Manajemen Rumah Sakit, 7(2), 93–101. https://doi.org/10.18196/jmmr.7261
  12. Rokhmah, D. (2013). Gender dan Penyakit Tuberkulosis : Implikasinya Terhadap Akses Layanan Kesehatan Masyarakat Miskin yang Rendah Gender and Tuberculosis : the Implication to Low Health Care Access for the. Kesmas, Jurnal Kesehatan Masyarakat Nasional, 7(37), 447–452. https://journal.fkm.ui.ac.id/kesmas/article/view/3
  13. Rosyid, A., Sabiti, F. B., & Roshani, D. F. (2019). Gambaran Pharmacovigilance dan Hubungan Faktor yang Mempengaruhi Reaksi Obat yang Tidak Diinginkan ( ROTD ) Pada Pasien Peresepan Obat Tuberculosis di Rumah Sakit Islam Sultan Agung Semarang Pharmacovigilance Overview and Affecting Factor Relation of Unwa. Jurnal Farmasi Indonesia, ISSN:1693-8615 EISSN:2302-4291, 16(1), 56–63. http://ejurnal.setiabudi.ac.id/ojs/index.php/farmasi-indonesia/article/download/497/464
  14. Sari, I. D., Yuniar, Y., & Syaripuddin, M. (2014). Studi Monitoring Efek Samping Obat Antituberkulosis Fdc Kategori 1 Monitoring Study On The Side Effects Of Tb Drugs Therapy Fdc Category 1 In. Media Litbangkes, 24(1), 28–35. https://media.neliti.com/media/publications/20692-ID-studi-monitoring-efek-samping-obat-antituberkulosis-fdc-kategori-1-di-provinsi-b.pdf
  15. Sari, Y. (2018). Gambaran Stigma Diri Klien Tuberkulosis Paru ( Tb Paru ) Yang Menjalani Pengobatan Di Puskesmas Malingping Self Stigma Of Pulmonary Tuberculosis Among Patients Seeking. Media Ilmu Kesehatan, 7(1), 43–50. https://ejournal.unjaya.ac.id/index.php/mik/article/download/223/221/
  16. Seniantara, I. K., Ivana, T., & Adang, Y. G. (2018). Pengaruh Efek Samping Oat ( Obat Anti Tuberculosis ) Terhadap Kepatuhan Minum. Jurnal Keperawatan Insan, 3(2). https://journal.stikessuakainsan.ac.id/index.php/jksi/article/view/98
  17. WHO. (2015). Global Tuberculois Report 2015 Executive Summary. World Health Organisation. https://www.who.int/publications/i/item/9789241565059