Article Sidebar

Submitted
Oct 6, 2021
Published
Apr 3, 2023
Download
Pdf
Statistic
Read Counter : 952 Download : 711

Downloads

Download data is not yet available.

Main Article Content

Abstract

Euphorbiaceae family plants are spread in Indonesia and empirically, have been used for a long time as medicine. This article review aims to discuss the pharmacological activities of several plants from the Euphorbiaceae family. This research was conducted by conducting a literature review limited to research in the form of scientific articles. The scientific article in question results from research reviewed and published in Indonesian and English. The steps in the search are divided into several stages, starting from identification, screening, eligibility, and data grouping. The articles used in this article review were obtained by searching the internet from online data search media/search engines such as Google/Google Scholar and journal provider sites such as PubMed, NCBI, and SINTA with the keywords "Euphorbiaceae plants," "Ethnopharmacology, "Ethnobotany and Ethnopharmacy," "Plant Activity and Effectiveness," "Euphorbiaceae family activity," and "Pharmacological activity of Euphorbiaceae. After determining the keywords, the next step is filtering multiple data or duplications and filtering the article's title, abstract, and keywords so that data can be determined to be used or not for the following review.This study is a literature review based on several national or international scientific articles about the pharmacological activity of Euphorbiaceae plants. The literature study found that some plants from the Euphorbiaceae family have pharmacological activities, and the most dominant are antimicrobial, antioxidant, and anti-inflammatory. Moreover, many other activities include analgesic, antipyretic, antithrombotic, anti-hypercholesterolemia, antihyperglycemic, antihistamine, diuretic, and antiseptic.

Keywords

Euphorbiaceae Medicinal plants Pharmacological activity

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

References

  1. Abe, R., & Ohtani, K. (2013). An Ethnobotanical Study of Medicinal Plants and Traditional Therapies on Batan Island. Journal of Ethnopharmacology, 145, 554–565.
  2. Adiyasa, M., & Meiyanti. (2021). Pemanfaatan Obat Tradisional di Indonesia: Distribusi dan Faktor Demografis yang Berpengaruh. Jurnal Biomedika Dan Kesehatan, 4(3), 130–138.
  3. Aljohani, A., Alhumaydhi, F., Rauf, A., Hamad, E., & Rashid, U. (2022). In Vivo Anti-Inflammatory, Analgesic, Sedative, Muscle Relaxant Activities and Molecular Docking Analysis of Phytovhemicals from Euphorbia pulcherrima. Hindawi: Evidence-Based Complementary and Alternative Medicine.
  4. Alyidrus, R., Ariastiwi, D. A., & Mardi, Y. (2019). Ekstrak Etanol Daun Meniran (Phyllanthus niruri L.) terhadap Mencit Jantan (Mus musculus) yang Diindukasi Asam Asetat Sebagai Analgetik. Media Farmasi, 15(1).
  5. Bahaman, N. A., Ahmad, R. R., Ahmad, N. Y., Mamun, A. A., Adzhar, N. S., & Basri, D. F. (2020). Medicinal Properties Screening of Mallotus paniculatus Extract. IMJM, 19(1), 6–12.
  6. Cesca, T., Faqueti, L., Rocha, L., Meira, N., Meyre-Silva, C., Souza, M., Quintao, N., Silva, R., Filho, V., & Bresolin, T. (2012). Antinociceptive, Anti-inflammatory and Wound Healing Features in Animal Models Treated with A Semisolid Herbal Medicine Based on Aleurites moluccana L. Willd. Euforbiaceae Standardized Leaf Extract Semisolid Herbal. Journal of Ethnopharmacology, 143.
  7. Chairani, A., & Harfiani, E. (2018). Efektivitas Getah Jarak Sebagai Antiseptik terhadap Pertumbuhan Staphylococcus aureus, Eschericia coli, dan Candida sp. secara In Vitro. Jurnal Kesehatan UNILA, 2(2), 84–92.
  8. Desnita, R., Luliana, S., & Anastasia, D. S. (2018). Antiinflammatory Activity Patch Ethanol Extract of Leaf Katuk (Sauropus androgynus L. Merr.). Jurnal Ilmu Kefarmasian Indonesia, 16(1).
  9. Fiandri, D., & Sutarto. (2020). Potensi Tanaman Patikan Kebo (Euphorbia hirta) sebagai Penyembuh Luka. Jurnal Medika Hutama, 2(1).
  10. Fitria, A., Suparmi, Upziah, D. N., & Lestari, S. L. W. (2018). Studi Aktivitas dan Analisis Kandungan Senyawa Antioksidan Batang Jatropha multifida L. Jurnal Ilmiah Farmasi, 12(2).
  11. Fitriansyah, S. N., Putri, Y. D., Haris, M., Ferdiansyah, R., Nurhayati, R., & Sari, Y. P. (2018). Aktivitas Antibakteri Ektsrak Etanol Buah, Daun, dan Kulit Batang Limpasu (Baccaurea lanceolata (Miq.) Mull. Arg.) dari Kalimantan Selatan. Jurnal Farmasi Indonesia, 15(2).
  12. Gosal, A. T., De Queljoe, E., & Suoth, E. J. (2020). Uji Aktivitas Antipiretik Ekstrak Etanol Daun Jarak Pagar (Jatropha curcas L.) pada Tikus Putih Jantan (Rattus norvegicus) Galur Wistar yang Diinduksi Vaksin DPT. PHARMACON, 9(3).
  13. Hadi, S., Wahyuono, S., Yuswanto, A., & Lukitaningsih, L. (2015). Penelusuran Fraksi Aktif Baccaurea lanceolata dari Kabupaten Tapin Kalimantan Selatan sebagai Antioksidan. PHARMACY, 12(2).
  14. Hamdiana, B., Jura, M., & Ratman. (2017). Penentuan Konsentrasi Efektif Ekstrak Tanaman Patikan Kebo (Euphorbia hirta) Merah dan Hijau dalam Melarutkan Kalsium. Jurnal Akademika Kimia, 6(4), 208–213.
  15. Hariyadi, B., & Ticktin, T. (2012). Uras: Medicinal and Ritual Plants of Serampas, Jambi Indonesia. Ethnobotany Research and Education, 10(133–150).
  16. Ibrahim, A. T., Sukenti, K., & Wirasisya, D. G. (2019). Uji Potensi Antimikroba Ekstrak Metanol Daun Kastuba (Euphorbia pulcherrima Willd.). Natural B, 5(1).
  17. Jannah, I., & Muhimmatin. (2021). Uji Obat Tradisional Daun Euporbia pulcherrima terhadap Penyakit Demam Typhoid. BIOMA : Jurnal Biologi Dan Pembelajaran Biologi, 6(1), 46–57.
  18. Junaidi, R. H., Ardana, M., & Rijai, L. (2016). Aktivitas Antioksidan Ekstrak dan Fraksi Kulit Batang Pila-Pila (Mallotus paniculatus) terhadap 1,1-Diphenyl-2 Picrylhidrazyl (DPPH). The 4th Mulawarman Pharmaceuticals Conferences, 303–309.
  19. Karim, K., Jura, M. R., & Sabang, S. M. (2015). Uji Aktivitas Antioksidan Ekstrak Daun Patikan Kebo (Euphorbia hirta L.). Jurnal Akademika Kimia, 4(2).
  20. Kementerian Kesehatan Republik Indonesia. (2018). Laporan Nasional RISKESDAS 2018.
  21. Lingga, I. S., Citraningtyas, G., & Lolo, W. A. (2014). Uji Efek Ekstrak Etanol Patikan Kebo (Euphorbia hirta Linn.) sebagai Diuretik pada Tikus Putih Jantan Galur Wistar (Rattus norvegicus sp.). PHARMACON, 3(3).
  22. Magdalena, S., Yuwono, B., & Dharmayanti, A. W. S. (2015). Pengaruh Daun Katuk (Sauropus androgynus (L.) Merr.) terhadap Waktu Perdarahan (Bleeding Time) pada Tikus Putih Wistar Jantan sebagai Alternatif Obat Antitrombotik. Jurnal Pustaka Kesehatan, 3(2).
  23. Majid, T., & Muchtaridi. (2018). Aktivitas Farmakologi Ekstrak Daun Katuk (Sauropus androgynus (L.) Merr.). Farmaka, 16(2).
  24. Mostofa, R., Ahmed, S., Begum, M., Rahman, M., Begum, T., Ahmed, S., Tuhin, R., Das, M., Hossain, A., Sharma, M., & Begum, R. (2017). Evaluation of Anti-inflammatory and Gastric Anti-ulcer Activity of Phyllanthus niruri L. (Euphorbiaceae) Leaves in Experimental Rats. BMC Complementary and Alternative Medicine, 17.
  25. Mukhriani, Ismail, A., Haeria, Syakri, S., & Fadiyah, N. (2017). Identifikasi Golongan Senyawa Antibakteri Fraksi Polar dan Non Polar Kulit Batang Kemiri (Aleurites moluccana L. Willd) dengan Metode Bioautografi Kontak. Jurnal Farmasi FIK UINAM, 6(1).
  26. Mulqie, L., & Anggadiredja, K. (2019). Aktivitas Antimikroba Fraksi Etil Asetat Daun Ceremai (Phyllanthus acidus (L.) Skeels) terhadap Bakteri Resisten Antimikroba dan Jamur dengan Metode KLT Bioautografi. Majalah Farmasetika, 4(1), 34–38.
  27. Mulyani, Y., Sumarna, R., & Patonah. (2020). Kajian Etnofarmakologi Pemanfaatan Tanaman Obat oleh Masyarakat di Kecamatan Dawuan Kabupaten Subang Provinsi Jawa Barat. Jurnal Farmasi Galenika, 6(1).
  28. Nastiti, K., & Hadi, S. (2020). Terpenoid Isolation from Baccaurea lanceolata Muell. Arg. Fruit. International Journal of Clinical Inventions and Medical Sciences, 2(1), 27–32.
  29. Ningsi, S., & Fadhilah, R. N. (2017). Uji Aktivitas Antimikroba Ekstrak Daun Jarak Pagar (Jatropha curcas Linn) terhadap Jamur Penyebab Kutu Air. Jurnal Farmasi FIK UINAM, 5(1).
  30. Novianti, D. (2017). Potensi dan Pengembangan Jenis Tanaman Obat di Desa Meranjat Kecamatan Indralaya Selatan. Sainmatika, 14(1), 45–52.
  31. Porto, C. R. C., Soares, A. L., Souza, T. P., PEtrovick, P. R., Lyra, I. L., Junior, F., Langassner, S. M., Ferreira, A. A., & Guerra, G. C. (2013). Anti-Inflammatory and Antinociceptive Activities of Phyllanthus niruri Spray-Dried Standardized Extract. Brazilian Journal of Pharmacognosy, 23(1), 138–144.
  32. Puspita, N., & Alhebshi, H. (2019). The Effect of Phyllanthus niruri L Extracts on Human Leukemic Cell Proliferation and Apoptisus Induction. Indonesian Journal of Pharmacy, 3(4), 241–251.
  33. Quintao, N., Rocha, L., Silva, G., Reichert, S., Claudino, V., Lucinda-Silva, R., Malheiros, A., Souza, M., Filho, V., Bresolin, T., Machado, M., Wagner, T., & Meyre-Silva, C. (2014). Contribution of α,β-Amyrenone to the Anti-Inflammatory and Antihypersensitivity Effects of Aleurites moluccana (L.) Willd. Hindawi : Biomed Research International.
  34. Rahman, M., Rana, S., Islam, A., Kumer, A., Hashem, A. K., Rahman, H., Mohaimenul, Biswas, T. K., & Sabbir, S. (2019). Antithrombotic and Anti-inflammatory Activities of Leaf Methanolic Extract of Euphorbia hirta Linn. International Journal of Complementary & Alternative Medicine, 12(4).
  35. Ramadheni, P., Mukhtar, H., & Pramono, D. (2017). Uji Aktivitas Antibakteri Ekstrak Etanol Daun Katuk (Sauropus androgynus (L.) Merr) terhadap Bakteri Staphylococcus aureus dan Eschericia coli dengan Metode Difusi Agar. Indonesian Natural Research Pharmaceutical Journal, 2(2).
  36. Sari, L. (2006). Pemanfaatan Obat Tradisional dengan Pertimbangan Manfaat dan Keamanannya. Majalah Ilmu Kefarmasian, 3(1).
  37. Selvi, S., & Bhaskar, A. (2012). Anti-inflammatory and Analgesic Activities of the Sauropus androgynus (L.) Merr. (Euphorbiaceae) Plant in Experimental Animal Models. Der Pharmacia Lettre, 4(3), 782–785.
  38. Singh, K., Rauniar, G., & Sangraula, H. (2012). Experimental Study of Neuropharmacological Profile of Euphorbia pulcherrima in Mice and Rats. Journal of Neurosciences in Rural Practice, 3(3).
  39. Singh, M., & Sudha. (2018). Evaluation of Phytochemical and Antibacterial Activity of Euphorbiaceae Members Against Human Pathogens. International Journal of Recent Scientific Research, 9(8).
  40. Siregar, D. A., Siregar, R. A., & Siregar, N. (2017). Analisis Fitokimia Tumbuhan Suku Euphorbiaceae sebagai Tumbuhan Berpotensi Obat di Bukit Simarsayang Kota Padangsidimpuan. Journal Education and Development, 6(2).
  41. Siregar, R. S., Hadiguna, R. A., Kamil, I., Nazir, N., & Nofialdi. (2020). Permintaan dan Penawaran Obat Tradisional di Provinsi Sumatera Utara. Jurnal Tumbuhan Obat Indonesia, 13(1).
  42. Sopiah, B., Muliasari, H., & Yuanita, E. (2019a). Skrining Fitokimia dan Potensi Aktivitas Antioksidan Ekstrak Etanol Daun Hijau dan Daun Merah Kastuba. Jurnal Ilmu Kefarmasian Indonesia, 17(1), 27–33.
  43. Sopiah, B., Muliasari, H., & Yuanita, E. (2019b). Skrining Fitokimia dan Potensi Aktivitas Antioksidan Ekstrak Etanol Daun Hijau dan Daun Merah Kastuba. Jurnal Ilmu Kefarmasian Indonesia, 17(1), 27–33.
  44. Sumarny, R., Yuliandini, & Rohani, M. (2013). Efek Anti-Inflamasi dan Anti-Diare Ekstrak Etanol Herba Meniran (Phyllanthus niruri L.) dan Daun Ungu (Graptophyllum pictum L. Griff). Seminar Nasional Dan Workshop Perkembangan Terkini Sains Dan Farmasi Klinik III.
  45. Syarif, A., & Usmar. (2014). Uji Efek Antiinflamasi Ekstrak n-Heksan Patikan Kebo (Euphorbia hirta L.) pada Mencit (Mus musculus). Jurnal Farmasi FIK UINAM, 2(1).
  46. Tatto, D., Dewi, N. P., & Tibe, F. (2017). Efek Antihiperkolesterol dan Antihiperglikemik Ekstrak Daun Ceremai (Phyllanthus acidus (L.) Skeels.) pada Tikus Putih Jantan (Rattus norvegicus) Hiperkolesterol Diabetes. Jurnal Farmasi Galenika, 3(2), 157–164.
  47. Wijaya, S., & Soegianto. (2017). Antidiarrheal Activity of the Combination of Ethanol Extracts of Turmeric Rhizomes, Gall Oak Leaves, Guava Leaves and Meniran Herbs. Jurnal Jamu Indonesia, 2(3), 96–101.
  48. Yensenem, O. B. M., Wuisan, J., & Awaloei, H. (2018). Uji Efek Analgesik Ekstrak Daun Jarak Pagar (Jatropha curcas L.) terhadap Tikus Wistar (Rattus norvegicus). Jurnal E-Biomedik, 5(1).
  49. Zamzani, I., & Triadisti, N. (2021). Limpasu Pericarpium :An Alternative Source of Antioxidant From Borneo With Sequential Maceration Method. Jurnal Profesi Medika: Jurnal Kedokteran Dan Kesehatan, 15(1), 60–68.