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Jun 20, 2022
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Apr 3, 2023
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Abstract

Mangrove plants in Indonesia are the largest in the world, both in terms of area quantity (+42,550 km2) and number of species (+45 species). Mangroves are a diverse group of salt tolerant plants that grow in intertidal tropical and subtropical forests and represent a rich biodiversity of plants, animals and microorganisms. Acanthus ilicifolius is one of the true mangrove plants which is used as medicine. This literature review aims to determine the study of benzoxazolinone compounds in jeruju plants (Acanthus ilicifolius) from previous studies and to determine the methods, plant parts and solvents used. The literature review method related to the jeruju plant (Acanthus ilicifolius) uses an electronic data base google scholar. Nuclear Magnetic Resonance (NMR) spectroscopy analysis method is one of the spectroscopic methods widely used in previous studies, because NMR spectroscopy is useful in determining the structure of a chemical compound, both proton (1H) and carbon (13C) NMR. Jeruju leaf extract contains alkaloids, flavonoids, polyphenols, phenyletanoid glycosides and coumarin compounds. The methanol fraction of jeruju leaf extract has a pharmacological effect to inhibit edema (inflammation). The extraction method used is maceration, because this method is simple method and most widely used. Meanwhile, the solvents that are more widely used are methanol and ethanol solvents.

Keywords

HPLC Acantus ilicifolius Benzoxazolinone

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References

  1. Apriasari, M. L. (2015). Aktivitas Antifungi Ekstrak Etanol dan Metanol Batang Pisang Mauli 100%. Jurnal Kedokteran Gigi Unej, 12(1), 26–29.
  2. Badaring, D. R., Sari, S. P. M., Nurhabiba, S., Wulan, W., & Lembang, S. A. R. (2020). Uji Ekstrak Daun Maja (Aegle marmelos L.) Terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus. Indonesian Journal of Fundamental Sciences, 6(1), 16–26. https://doi.org/10.26858/ijfs.v6i1.13941
  3. Bhattarai, B., Steffensen, S. K., Staerk, D., Laursen, B. B., & Fomsgaard, I. S. (2022). Data-dependent Acquisition-mass Spectrometry Guided Isolation of New Benzoxazinoids From The Roots of Acanthus Mollis L. International Journal of Mass Spectrometry, 474, 1–10. https://doi.org/10.1016/j.ijms.2022.116815
  4. Cai, R., Chen, S., Long, Y., Li, C., Huang, X., & She, Z. (2017). Depsidones from Talaromyces stipitatus SK-4, an endophytic fungus of the mangrove plant Acanthus ilicifolius. Phytochemistry Letters, 20, 196–199. https://doi.org/10.1016/j.phytol.2017.04.023
  5. Kanchanapoom, T., Kamel, M. S., Kasai, R., Picheansoonthon, C., Hiraga, Y., & Yamasaki, K. (2001). Benzoxazinoid glucosides from Acanthus ilicifolius. Phytochemistry, 58(4), 637–640. https://doi.org/10.1016/S0031-9422(01)00267-9
  6. Mukhriani. (2014). Ekstraksi, Pemisahan Senyawa, Dan Identifikasi Senyawa Aktif. Jurnal Kesehatan, 7(2), 361–367.
  7. Sayuti, M. (2017). Pengaruh Perbedaan Metode Ekstraksi, Bagian Dan Jenis Pelarut Terhadap Rendeman Dan Aktifitas Antioksidan Bambu Laut (Isis Hippuris). Technology Science and Engineering Journal, 1(3), 166–174.
  8. Suryati, Husni, E., Astuti, W., & Ranura, N. (2018). Karakterisasi dan Uji Sitotoksik Daun Jeruju (Acanthus ilicifolius). Jurnal Sains Farmasi & Klinis, 5(3), 207–211.
  9. Tian, X. Q., Ke, L. N., Chen, Q. H., Zeng, X. H., Wang, H. M., & Li, P. (2021). Synthesis of Acanthus Ilicifolius Linn Alkaloid 2-Benzoxazolinone Derivative and Its Effect on Cervical Cancer C-33A Cells. IOP Conference Series: Earth and Environmental Science, 858(1), 1–7. https://doi.org/10.1088/1755-1315/858/1/012014
  10. Utami, K., Wati, J., Veronika, S., Astuti, R. W., & Rahimuddin. (2020). Pengaruh Penggunaan Aplikasi Chemdraw Sebagai Belajar Kimia Terhadap Peningkatan Hasil Belajar Mahasiswa Pada Materi spektroskopi NMR. KATALIS Jurnal Penelitian Kimia Dan Pendidikan Kimia, 3(1), 24–30.
  11. Verma, H., & Silakari, O. (2018). Benzoxazolinone: Perancah Dengan Signifikansi Farmakologis Beragam. Key Heterocycle Cores for Designing Multitargeting Molecules, 343–367. https://doi.org/10.1016/b978-0-08-102083-8.00010-8
  12. Yin, H., Zhang, S., Luo, X., & Liu, Y. (2008). Preparative isolation and purification of two benzoxazinoid glucosides from Acanthus ilicifolius L. by high-speed counter-current chromatography. Journal of Chromatography A, 1205, 177–181. https://doi.org/10.1016/j.chroma.2008.08.010
  13. Zhao, D., Xie, L., Yu, L., An, N., Na, W., Chen, F., Li, Y., Tan, Y., & Zhang, X. (2015). New 2-Benzoxazolinone Derivatives with Cytotoxic Activities from the Roots of Acanthus ilicifolius. Chemical and Pharmaceutical Bulletin, 63(12), 1087–1090. https://doi.org/10.1248/cpb.c15-00597